Biography

Personal Data

Family Name: Mahmoud Youssef  Moustafa

First Name: Amal

Nationality: Egyptian

Martial Status: Married

Title: Prof. Doctor

Current Position: Chemistry Department-Faculty of Science- Port-said University, Port-said, Egypt. 

E-Mail: moustafaamm@yahoo.com

             ammoustafa@kfu.edu.sa

             a.moustafa@sci.psu.edu.eg

Educational Qualification

Demonstrator: (Resolution No. 355), 3-4-1994, Chemistry Department, Faculty of Science- Suez Canal University, Ismailia- Egypt.

Assistant Lecturer: (Resolution No. 95), 25-1-1996, Chemistry Department, Faculty of Science- Suez Canal University, Chemistry Department, Faculty of Science- Suez Canal University, Ismailia- Egypt. 

Lecturer: (Resolution No. 158), 22-1-2002,  Chemistry Department, Faculty of Science- Suez Canal University, Ismailia- Egypt.

Lecturer: (Resolution No. 761), 29-7-2008, Chemistry Department, Faculty of Science- Port Said University, Port Said- Egypt. 

Associate Professor: (Resolution No. 1716), 27-11-2019, Chemistry Department, Faculty of Science- Port Said University, Port Said – Egypt.

Professor Doctor: (Resolution No. 238), 27-1-2026, Chemistry Department, Faculty of Science- Port Said University, Port Said – Egypt.

Academic And Professional Experience

Awards

1. Governmental Scholarship for Ph.D., in Environmental Chemistry and Toxicology Laboratory, Texas, Texas Southern University, Houston, Texas, USA, for two years 11-2-1997 to 1-11-1999.
2. Personal Post-Doctorate Scholarship, in HEJ-Research Institute of Chemistry, Karachi University, Karachi, Pakistan, for Seven months from 8-13-2004 to 3-18-2005.
3. Loan to Saudi Arabia, Faculty of science, Chemistry dept., King Faisal University, Saudi Arabia, 27-6-2006 to 1-9-2016.

Project Participation

Project between Suez Canal University (Chemistry Department, faculty    of Science) and National Research Center (Chemistry of Medicinal Plants section).

Title: Exploitation and Evaluation of Medicinal and Wild Plants Growing      in Sinai, 1992-1995. 

Publications

1. Amal M. Youssef Moustafa*, Ahmed I. Khodair, Faiza M. Hammouda, and Husseiny A. Husseiny (2007): Phytochemical investigation and a-cellulose content of Gazania splendens MOORE. Research Journal of Phytochemistry, 1(1): 21-32. http://dx.doi.org/10.3923/rjphyto.2007.21.32.
2. Amal M. Youssef Moustafa*, Ahmed I. Khodair, Faiza M. Hammouda, Husseiny A. Husseiny (2007): Phytochemical and toxicological studies of Zygophyllum album L. F. Journal of Pharmacology and Toxicology, 2(3): 220-237. http://dx.doi.org/10.3923/jpt.2007.220.237.
3. Amal M. Youssef Moustafa*, Ahmed Ismail Khodair and Mahmoud A. Saleh, 2007, Phytochemical investigation and toxicological studies of lipid constituents isolated from Leptadenia pyrotechnica. Journal of Pharmacology and Toxicology, 2(8): 681-697. http://dx.doi.org/10.3923/jpt.2007.681.697. (Impact Factor: 2.285).
4. Amal M. Youssef Moustafa*, Ahmed I. Khodair, and Mahmoud A. Saleh (2009): Isolation, structural elucidation of flavonoid constituents from Leptadenia pyrotechnica and evaluation of their toxicity and antitumor activity. Pharmaceutical Biology, 47(6): 539-552. http://dx.doi.org/10.1080/13880200902875065. (Impact Factor: 2.971, Q1).
5. Amal M. Youssef Moustafa*, Ahmed Ismail Khodair and Mahmoud Ahmed I. Khodair, and Mahmoud A. Saleh (2009): Structural elucidation and evaluation of toxicity and antitumor activity of cardiac glycosides isolated from Leptadenia pyrotechnica. Pharmaceutical Biology, 47(9): 826-834. (Impact Factor: 2.971, Q1).
6. Amal M. Youssef Moustafa*, Ahmed I. Khodair, and Mahmoud A. Saleh (2009): GC-MS investigation and toxicological evaluation of alkaloids from Leptadenia pyrotechnica. Pharmaceutical Biology, 47(10): 994-1003. http://dx.doi.org/10.1080/13880200902973761. (Impact Factor: 2.971, Q1).
7. Amal M. Youssef Moustafa*, Ahmed I. Khodair, and Mahmoud A. Saleh (2011): Potato Disc Bioassay and Cytotoxic Effect of Leptadenia pyrotechnica: Comparative study of diverse extracts Pakistan Journal of Biological Sciences, 14(18): 882-886. http://dx.doi.org/10.3923/pjbs.2011.882.886. (Impact Factor: 0.95).
8. Simon F. Kouam, Shamsun Nahar Khan, Karsten Kron, Bonaventure T. Nagadjui, Deccaux G. W. F. Kapche, Diane B.Yapna, Seema Zareem, Amal M. Y. Moustafa, and M. Iqbal Choudhary (2006):   α-Glucosidase inhibitory anthranols, kenganthranols A-C, from the stem bark of Harungana madagascariensis. Journal of Natural products, 69(2): 229-233. https://doi.org/10.1021/np050407n. (Impact Factor: 4.803, Q1).
9. Amal M. Youssef Moustafa*, Simeon F Kouam, Aisha Kulsoom, Asma Ejaz and Shamsher Ali, Shazia Anjum and M. Iqbal Choudhary (2007): Phytochemical investigation and biological evaluation of Schinus terebinthifolius. Research Journal of Phytochemistry, 1(1): 1-11. https://scialert.net/abstract/?doi=rjphyto.2007.1.11. (Impact Factor:  4.072).
10. Amal M. Youssef Moustafa* (2007): Chemical composition and antifungal activity of essential oil from Schinus terebinthifolius of Egyptian origin. International Journal of Essential Oil Therapeutics, 1: 91-95.
11. Amal M. Youssef Moustafa*, Jehan A. El-Shoubaky, Essam Abd E. Salem (2008): Comparative phytochemical investigation of hydrocarbons content on some marine seaweeds algae. Research Journal of Phytochemistry, 2(1): 10-17. http://dx.doi.org/10.3923/rjphyto.2008.10.17.
12. Jehan A. El-Shoubaky, Amal M. Youssef Moustafa*, and Essam Abd E. Salem (2008): Comparative phytochemical investigation of beneficial essential fatty acids on a variety of marine seaweeds algae. Research Journal of Phytochemistry, 2(1): 18-26.
13. A.M.Y. Moustafa*, S.H. Ahmed, Z.I. Nabil, A.A. Hussein, M.A. Omran (2010): Extraction and phytochemical investigation of Calotropis procera: Effect of plant extracts on the activity of diverse muscles (in vitro study). Pharmaceutical Biology, 48(10): 1080-1090. https://doi.org/10.3109/13880200903490513. (Impact Factor: 2.971, Q1).
14. M. H. Sherif and Amal M.Yossef (2015): Synthesis and anticancer evaluation of some fused coumarino-[4,3-d]-pyrimidine derivatives. Research on Chemical Intermediates, 41:383-390. (Impact Factor:  3.134, Q2).
15. Amal Mahmoud Youssef Moustafa* (2017): Synthesis, Characterization and Biological Evaluation of Some Heterocyclic Compounds Based on 3-methoxy-2-hydroxybenzaldehyde. Imperial Journal of Interdisciplinary Research, 3(9): 348-357.
16. Amal Mahmoud Youssef Moustafa* (2017): Synthesis, Characterization, Biological Activity of 4-Oxo-imidazolidin-2-thione Derivatives. Current Research in Chemistry, 9(1): 1-13. https://doi.org/10.3923/crc.2017.1.13. (Impact Factor:  4.714).
17. Elsherbiny Hamdy ELsayed, Amal Y. Moustafa and Sara A.A., EL-Ata (2018): Synthesis of New 2-N-Substituted Amino-5-aryl-1,3-thiazoles as Antitumor Agents. Latin American Journal of Pharmacy, 37(8): 1594-1601. (Impact Factor:   0.229).
18. Amal Mahmoud Youssef Moustafa*, Safyah B. Bakare (2019): Synthesis of Some Hybrid 7‑Hydroxy Quinolinone Derivatives as Anti Breast Cancer Drugs.  Research on Chemical Intermediates, 45(7): 3895–3912. https://doi.org/10.1007/s11164-019-03827-y. (Impact Factor:  2.203, Q2).
19. Amal Mahmoud Youssef Moustafa* (2019): In vitro Anti leukemia Cancer Activity of some Novel Pyrazole Derivatives and Pyrazoles Containing Thiazole Moiety. American Journal of Heterocyclic Chemistry, 5(3): 55-70. https://doi.org/10.11648/j.ajhc.20190503.12.
20. Zohour I Nabil, Aida A. Hussein, Amal M. Youssef Moustafa, Sherifa H. Ahmed and Mohamed Alaa A. Omran (2006): Assessment of the therapeutic effect of Calotropis procera extract and Digoxin on mycocardial pathophysiology, an experimental study. Egyptian Journal of Natural Toxins, 3: 51-76. http://dx.doi.org/10.3109/13880200903490513. (Impact Factor:  1.539).
21. Islam Zaki, Amal M. Y. Moustafa, Botros Y. Beshay, Reham E. Masoud, Mohammed A. I. Elbastawesy, Mohammed A. S. Abourehab & Mohamed Y. Zakaria (2022): Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and antiproliferative activity. Journal of Enzyme Inhibition and Medicinal Chemistry, 37(1): 2679-2701. https://doi.org/10.1080/14756366.2022.2116016. (Impact Factor 4.31, Q1).
22. Lina M. A. Abdel Ghany, Botros Y. Beshay, Amal M. Youssef Moustafa, Ali Hassan Ahmed Maghrabi, Eman Hussain Khalifa Ali, Rasha Mohammed Saleem, Islam Zaki & Noha Ryad (2023): Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNFα production inhibitors via upregulating Nrf2/HO-1, downregulating AKT/mTOR signalling pathways and downregulating NF-κB in LPS induced macrophages, Journal of Enzyme Inhibition and Medicinal Chemistry, 38(1): 2243551. https://doi.org/10.1080/14756366.2023.2243551. (Impact Factor: 5.756, Q1).
23. Dalal Nasser Binjawhar, Fawziah A. Al-Salmi, Maha Ali Alghamdi, Arwa sultan Alqahtani, Eman Fayad, Rasha Mohammed Saleem, Islam Zaki, and Amal Mahmoud Youssef Moustafa (2024): Design, Synthesis, and Biological Evaluation of Newly Synthesized Cinnamide-Fluorinated Containing Compounds as Bioactive Anticancer Agents. American Chemical Society Omega (ACS Omega), 9(16): 18505–18515. https://doi.org/10.1021/acsomega.4c00847. (Impact Factor: 4.26, Q2).
24. Amal M. Yousesf Moustafa*, Mohamed Abdel-Monem, Mohamed E. Mostafa, Mamdouh Abdel-Mogib, and Marwa Rabee Abdel-Hak. (2025): Antitumor Sucrose esters of aryldihydronaphthalene-type lignans from Moltkiopsis ciliata (Forssk.) Plant Extracts. Natural Products Research, Taylor & Francies, 39(16):4533-4543. https://doi.org/10.1080/14786419.2024.2341307. (Impact Factor: 2.488, Q2).
25. Amal M. Youssef Moustafa, Mona M. Fawzy, Mahmoud S. Kelany, Yasser A. Hassan, Reda F.M. Elsharaawy, Fatma H.A. Mustafa (2024):  Synthesis of new quaternized chitosan Schiff bases and their N-alkyl derivatives as antimicrobial and anti-biofilm retardants in membrane technology. International Journal of Biological Macromolecules, 267(2): 131635. https://doi.org/10.1016/j.ijbiomac.2024.131635. (Impact factor: 7.7, Q1).
26. Amal M. Y. Moustafa, Maha M. A. El-Damrany, Mohamed E. Mostafa, Mamdouh Abdel-Mogib. (2025). New Bioactive Phytoconstituents, Antioxidant and Cytotoxic Activities of Acalypha wilkesiana Müll Arg. Egyptian Journal of Chemistry. 68(1). https://doi.org/10.21608/ejchem.2025.381913.11712.  (Article in press) (Impact factor: 1.2, Q3).
27. Rana T. Rashwan, Amal M.Youssef Moustafa, Hanan A.A. Taie, Mohamed Marzouk. (2025). Codiaeum variegatum Zanzibar (Pictum spot): LC-MS/MS Phytochemical Profile and In vitro Antioxidant and Antitumor Activities. Egyptian Journal of Chemistry, 67(9): 339-357. https://doi.org/10.21608/ejchem.2024.259570.9125. (Impact factor: 1.2, Q3).
28. Maha Ali Alghamdi, Mustafa R. Abdulbaqi, Rana Abdullah Alghamdi, Eman Fayad, Dalal Nasser Binjawhar, Hanadi A. Katouah, Abdullah Yahya Abdullah Alzahrani and Amal M. Youssef Moustafa. (2025). Design, synthesis and anticancer evaluation of naphthalen-1-yloxyacetamide derivatives against MCF-7 cells. Royal Society of Chemistry-Advances, 15(43): 36152–36164. https://doi.org/10.1039/D5RA06524K. (Impact factor: 4.6, Q2).
29. Eman M. Radwan, Elsherbiny H. Elsayed, Mohamed Abd El-Moneim, Amal M. Youssef Moustafa (2021): Design, Synthesis, and Anti-Breast Cancer Activity of Some Hybrid Molecules Containing Coumarin Moiety.  Russian Journal of Bioorganic Chemistry, 47(1): 149-157. http:// DOI:10.1134/s1068162021010180. (Impact Factor: 0.216, Q4).
30. Eman Mossad Mahmoud Radwan, El-Sherbiny Hamdy El-Sayed Yuossif, Mohamed Abd El-Moneim Mahmoud Mohamed, Amal Mahmoud Youssef Moustafa (2021): Synthesis and Biological Evaluation of Some New 3,4-Disubstituted Coumarin Derivatives as Anticancer Agents. Indian Journal of Heterocyclic Chemistry, 31(1): 101-111. https://connectjournals.com/01951.2021.31.101.  (Impact Factor: 0.3).
31. Amal Mahmoud Youssef Moustafa*, Maha Mohamed Abd El-Hamid El-Damrany, Magdy M.Youssef (2023): The Effect of Iron Oxide Nanoparticles of Acalypha wilkesiana Ethyl Acetate Extract on Ehrlich Ascites Carcinoma Cells. Anti-cancer Agents in Medicinal Chemistry (Anticancer Agents Med. Chem.), 23(14): 1652-1669. http://dx.doi.org/10.2174/1871520623666230517100427. (Impact Factor: 2.8, Q3).
32. Amal Mahmoud Youssef Moustafa*, Maha Mohamed Abd El-Hamid El-Damrany, Mohamed Mohamed Ibrahim El-Sayed, Magdy M.Youssef (2023): Studies of Phytochemistry, Bioassay, and Synthesis of Magnetite Nanoparticles for Acalypha wilkesiana Müll Mosaica Plant. Alfarama Journal of Basic & Applied Sciences, 4(2): 181–220. https://dx.doi.org/10.21608/ajbas.2022.162361.1122.
33. Marwa Rabee Abdel-Hak, Mamdouh Abdel-Mogib, Mohamed E. Mostafa, Mohamed Abdel-Monem1 and Amal M. Yousesf Moustafa (2023): GC/MS Volatile Constituents Analysis and Anticancer Activity of Moltkiopsis ciliata (Forssk.). Alfarama Journal of Basic & Applied Sciences, 4(1): 1-12. https://dx.doi.org/10.21608/ajbas.2022.152453.1117.
34. Amal M. Y. Moustafa, Mamdouh Abdel-Mogib, Mohamed E. Mostafa, Lamiaa A. A. Barakat, Asmaa M. Shaalan (2023): Antioxidant, Antibacterial and GC/MS volatiles profiling of Alhagi graecorum Boiss. Alfarama Journal of Basic & Applied Sciences, 4(2): 171-180. https://dx.doi.org/10.21608/ajbas.2022.156399.1118.
35. El Ghany, Y.I.A., Tawfik, M.M., El Bous, M., Gomaa, I., Moustafa, A.M.Y., Hosny, N.M. (2024). Sesuvium sesuvioides (Fenzl) Mediated Synthesis of Zinc Oxide and Copper Oxide Nanoparticles and Their Potential Cytotoxic and Apoptotic Effects. pp 309–330. In: El-Dossoki, F., Hassan, M., Shehata, A. (eds) Proceedings of The First International Conference on Green Sciences. ICGS 2023. Earth and Environmental Sciences Library. Springer, Cham. https://doi.org/10.1007/978-3-031-62672-2_18.
36. Reem M. Elbana, Hanan A. A. Taie, Amal M. Youssef Moustafa, Mohamed Marzouk (2024). LC-MS/MS analyses of Khaya grandifoliola and in vitro Antioxidant Activity and Cytotoxicity of Khaya senegalensis and Khaya grandifoliola against Ehrlich Ascites Carcinoma Cells. Egyptian Journal of Chemistry, 67(9): 309-325. https://doi.org/10.21608/ejchem.2024.259569.9124. (Impact factor: 1.2, Q3).