Biography

Prof. Omar Mohammed Aly, Ph.D.
Vice Dean for Graduate Studies and Research
Professor of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Egypt

Born on August 8, 1967, Prof. Omar Mohammed Aly is an accomplished Egyptian scientist and academic specializing in medicinal and pharmaceutical chemistry. He currently serves as Vice Dean for Graduate Studies and Research and Professor of Medicinal Chemistry at the Faculty of Pharmacy, Port Said University.

Prof. Aly earned his B.Sc. in Pharmaceutical Sciences from Zagazig University in 1990, followed by an M.Sc. in Medicinal Chemistry (1999) and a Ph.D. in Medicinal Chemistry from Minia University (2003).

I further advanced my expertise through a postdoctoral fellowship at the University of Georgia, USA (2006–2007), where I focused on the design and synthesis of nucleoside analogs with potential anti-HBV activity.

Throughout my career, I have held key academic and administrative roles, including Head of the Department of Medicinal and Organic Chemistry at Minia University (2009–2015) and Head of the Pharmaceutical Chemistry Department at Albaha University, Saudi Arabia (2017–2019), where I also served as College Coordinator. I have extensive teaching experience in medicinal and organic chemistry across Egypt and Saudi Arabia, contributing significantly to undergraduate and postgraduate education.

My research spans anticancer drug discovery, antiviral agents, natural products, molecular docking, and drug design, with more than 60 international publications in high-impact journals. I have supervised numerous graduate students, guiding over 19 master’s theses and 5 Ph.D. dissertations.

I have  been recognized with several prestigious awards and grants, including the Prof. Ehab Hassan Esmail Award for Excellence in Ph.D. Research (2005), multiple research grants from Egypt and Saudi Arabia, and Minia University Awards for International Publications. I have also been listed in Marquis Who’s Who in the World.

In addition to my research contributions, Prof. Aly is highly active in scientific publishing and peer review. He serves on the editorial boards of leading journals, including European Journal of Medicinal Chemistry, Talanta, and Molecules. I am also Editor-in-Chief of the journal Octahedron Drug Research and have acted as Guest Editor for Current Topics in Medicinal Chemistry.

I have presented my work at numerous international conferences in Egypt, the USA, and the Gulf region, and has hosted scientific webinars, such as on Advanced Mass Spectrometry (2025).

I am a member of several professional associations, including the American Chemical Society, the Egyptian Pharmacists’ Syndicate, and the Egyptian Pharmaceutical Sciences Society.

My career reflects a strong commitment to advancing medicinal chemistry research, fostering international collaborations, and mentoring the next generation of pharmaceutical scientists.

Educational Qualification

Bsc of Pharmaceutical Sciences, Zagazig University, Egypt. 1990

Master of Medicinal Chemistry, Zagazig University, Egypt. 1999

PhD of Medicinal Chemistry, Minia University, Egypt 2003

Postdoctoral Fellowship, University of Georgia, USA, 2007

Academic And Professional Experience

Visitor instructor:

Misr international university (MIU), Cairo. September 2003 - June 2005

Visitor scientist: Wake Forest University, Winston Salem, North Carolina, USA, Dec.    2009.

Visitor Professor: Albaha University, College of Clinical Pharmacy, KSA (Jan. 2015 to June 2020)

Teaching medicinal chemistry for undergraduate and post graduate students: Department of medicinal chemistry, faculty of pharmacy, Minia university, Egypt, from Feb. 25, 2003 – Jan 30, 2015.

Teaching organic chemistry for undergraduate and postgraduate students: Department of medicinal chemistry, faculty of pharmacy, Minia university, Egypt, from Feb. 25, 2003 – Jan 30, 2015.

Teaching Quality control of drug substances (raw materials and finished products).

Teaching medicinal chemistry to undergraduate students, college of clinical pharmacy, Albaha University, KSA.

Teaching organic chemistry (instrumental analysis) for undergraduate students, college of clinical pharmacy, Albaha University, KSA.

Head of the  medicinal and organic chemistry department, faculty of pharmacy, Minia university, Egypt, from September 9, 2009, till Jan 30, 2015.

Head of the pharmaceutical chemistry department, college of clinical pharmacy, Albaha University, KSA, 2017-2019.

College coordinator, college of clinical pharmacy, Albaha University, KSA, 2017-2019.

Memberships of professional associations:

Member of the Egyptian Pharmacists'   Syndicates.

Member of the Egyptian pharmaceutical sciences society.

Member of the American Chemical Society.

Conferences:

- 75th years of Fulbright, Egypt “from lab to market”, Nov., 4, 2024.

- DU-Pharm 2023, 2nd international conference of the faculty of pharmacy

Poster presenter at Al-Azhar 4th International Conference for Pharmaceutical and Biological sciences in Feb. 2006. Al-Azhar University, Cairo, Egypt.

- Two Posters presentations at the 32nd of pharmaceutical sciences, Cairo University, Cairo, Egypt.

- Poster presentation at Assiut 9th International Conference for pharmaceutical sciences 12-13 March 2014, Assiut University, Egypt.

- Poster presentation at 247th ACS National Meeting & Exposition, Dallas, TX, United States, March 16-20, 2014.

-  Poster presentation at 3rd Annual Texas Screening Alliance for Cancer Therapeutics conference titled "New Frontiers in Therapeutic Agents: Successes in Drugging the Undruggable "April 16-17, 2014, Houston, Texas, USA.

- Poster presentation "Study about the familiarity with the proper uses of antibiotics by the general public in Albaha region, Saudi Arabia" at DUPHAT, Dubai, UAE, 1438 H.

   -  Webinar host and presenter titled(Advanced Mass Spectrometry) 1-2/8/2025

Awards and grants:

- Prof. Ehab Hassan Esmail Award for distinction in the Ph.D. thesis. April 2005                 

-  Grant from science and technology development fund, Egypt (project ID:  2943). The amount of funds was about USD: 100,000 for two years.

-  Minia University awards for distinct international publications, 2013 to 2020.

- Grant from Albaha University, Saudi Arabia (project # 53/1436). The amount of funds is USD 11,000 for one year.

 - Grant from Al Baha University (project # 108/1438). The amount of funds is USD 14,000 for one year.

- Award of Membership of Marquis Who's Who in The World.

Peer Reviewer& Editorial Boards Membership

- European Journal of Medicinal Chemistry: 100 Completed Reviewer Assignments.

-  Talanta: Total 55 Completed Reviewer Assignments.

- Reviewing a five Research projects, King Faisal University, Saudi Arabia.

- Arbitration of the Port Said University's encouragement and appreciation awards (2023)

- Plos one: (Journal of Impact factor > 3) 1 reviewer assignment.

- Anticancer agents in medicinal chemistry, 1 reviewer assignment.

- Editorial board membership of Texas J. of analytical and pharmaceutical chemistry.

- Journal of the Serbian Chemical Society.

- Journal of Helvetica Chimica Acta, Switzerland.

- Journal of bioorganic chemistry.

- Journal of Medicinal Chemistry Research.

- Journal of the Chemical Society of Pakistan

- Journal of Bioorganic and Medicinal Chemistry.

- Journal of Bioorganic and Medicinal Chemistry Letters.

- Journal of Bioorganic Chemistry.

- European J of medicinal chemistry reports.

- Heliyon Journal.

- Egyptian Journal of Chemistry.

- Molecules

- Journal of Molecular Structure

- Zagazig Journal of Pharmaceutical Sciences

- Editor in chief: Octahedron Drug Research, https://odr.journals.ekb.eg/

- Guest Editor: Current Topics of Medicinal Chemistry.

Editorial (Thematic Issue: Novel Approaches to the Discovery of Selective and Targeted Anticancer Agents) VOLUME: 16, ISSUE: 22, Year: 2016, Page: [2431 - 2431]

Editor in chief, Octahedron Drug Research.

Theses Supervisions:

Advisor for 19 master theses (14 completed).

Advisor for 5 Ph.D. theses (3 completed).

Panel membership for reviewing masters and Ph.D. theses in Saudi Arabia and Egypt.

Quality assurance and accreditation: 22 Workshops

Membership of different quality assurance and accreditation committees at both Minia University, Egypt, and Albaha University, KSA.

Publications

1. Al-Katib, M.., Saber, Abdullah A., Aly, O.,, Wedad M. Abdelraheem, Eman Z. Attia, Iman A.M. Abdel Rahman, Maha Alharbi, Fauzeya Mateq Albalwe, Amr Elkelish, Rushdi, M., Abdelmohsen, U., Sabe, H, Pereira, L.,  Cosmopolitan but still untapped: Antimicrobial, antibiofilm and in silico molecular docking study on Caulerpa racemosa, Dictyopteris polypodioides and Padina pavonica, Algal Research, Volume 2025, 85,  103837 https://doi.org/10.1016/j.algal.2024.103837
2. Abdelraheem, A., Aly, O., Mohamed, M., Mohassab, A. HDAC as a cancer target: Various scaffolds based on HDAC inhibitors and an overview of their advances. Octahedron Drug Research, 2024; 5(1): 22-50. doi: 10.21608/odr.2024.274567.1037
3. Soudi, A., Bender, O., Celik, I., El-Hafeez, A. A. A., Dogan, R., Atalay, A., Elkaeed, E. B., Alsfouk, A. A., Abdelhafez, E. M. N., Aly, O. M., Sippl, W., & Ali, T. F. S. (2024). Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor. Pharmaceuticals (Basel, Switzerland), 17(5), 659. https://doi.org/10.3390/ph17050659
4. Attia, E.Z., Abdel-Rahman, I.A.M., Aly, O.M. et al. In Vitro Cytotoxic Potential of Ethanol Extract of Dictyopteris acrostichoides Against Human Cancer Cells. Rev. Bras. Farmacogn. 34, 212–216 (2024). https://doi.org/10.1007/s43450-023-00474-8
5. Aya Soudi; Shimaa M.N. Abdelhafez; Omar M. Aly; Taha F.S. Ali. "Indolin-2-one based scaffold for the development of multi- kinase inhibitor: Focus on sunitinib as an anticancer agent". Octahedron Drug Research, 4, 1, 2024, 1-10. doi: 10.21608/odr.2023.225166.1028
6. Moamen A. Hassanin; Muhamad Mustafa; Heba A. Hassan; Eman A Beshr; Ahmed T. M. Elshennawy; Omar M. Aly. "Hydantoin derivatives: A review on their anticancer activities". Octahedron Drug Research, 4, 1, 2024, 61-74. doi: 10.21608/odr.2023.232555.1029
7. Metwally, K., Abo-Dya, N.E., Hamdan, A.M.E. et al. Investigation of Simultaneous and Sequential Cooperative Homotropic Inhibitor Binding to the Catalytic Chamber of SARS-CoV-2 RNA-dependent RNA Polymerase (RdRp). Cell Biochem Biophys 81, 697–706 (2023). https://doi.org/10.1007/s12013-023-01163-y
8. Maiiada H. Nazmy, Dalia H. Abu-baih, Mahmoud A. Elrehany, Muhamad Mustafa, Omar M. Aly, Azza A. K. El-Sheikh, Moustafa Fathy. Assessing the Antiproliferative Potential of a Novel Combretastatin A4 Derivative via Modulating Apoptosis, MAPK/ERK and PI3K/AKT Pathways in Human Breast Cancer Cells. Front. Biosci. (Landmark Ed) 2023, 28(8), 185. https://doi.org/10.31083/j.fbl2808185
9. Alanazi J, Bender O, Dogan R, Malik JA, Atalay A, Ali TFS, Beshr EAM, Shawky AM, Aly OM, Alqahtani YNH, Anwar S. Combination of an Oxindole Derivative with (-)-β-Elemene Alters Cell Death Pathways in FLT3/ITD+ Acute Myeloid Leukemia Cells. Molecules. 2023 Jul 6;28(13):5253. doi: 10.3390/molecules28135253. 
10. Eman Zekry Attia, Iman A. M. Abdel-Rahman, Omar M. Aly et al. EGFR, and VEGFR inhibitory activities of the crude extract from marine algae Dictyopteris acrostichoides supported by in silico analysis and metabolic profiling, 10 May 2023, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-2854258/v1]
11.  O. Bender, M. E. Shoman, T. F. S. Ali, R. Dogan, I. Celik, A. Mollica, M. I. A. Hamed, O. M. Aly, A. Alamri, J. Alanazi, N. Ahemad, S. H. Gan, J. A. Malik, S. Anwar, A. Atalay, E. A. M. Beshr, Arch. Pharm. 2023; 356:e2200407. https://doi.org/10.1002/ardp.202200407
12. Sayed Aliul Hasan Abdi, Abuzer Ali, Shabihul Fatma Sayed, Amena Ali, Shaivad Shabee Hulhasan Abadi, Abu Tahir, Mohd Amir Afjal, Hina Rashid, Omar M. Aly & Sumathi Nagarajan (2023) Potential of paracetamol for reproductive disruption: molecular interaction, dynamics, and MM-PBSA based in-silico assessment, Toxicology Mechanisms and Methods, 33:5, 349-363, DOI: 10.1080/15376516.2022.2137872
13. Abdelfattah Hassan; Mostafa M. Badran; Heba A. Hassan; Dalia Abdelhamid; Omar Aly. "Design, synthesis in vitro and in vivo evaluation of new diaryltriazoles carboxylic and hydroxamic acid derivatives as inhibitors of tumor necrosis alpha converting enzyme (TACE)". Octahedron Drug Research, 2, 1, 2023, 44-62. doi: 10.21608/odr.2023.179650.1020
14. Shimaa Naguib; Omar Aly; Gamal Abourhma; Stephen King; Freddie Salsbury; Karin Scarpinato; Andrew Diamanduros. "Synthesis, Molecular Modeling and Anticancer Activity of New Rescinnamine Derivatives as MMR-Inducers". Octahedron Drug Research, 2, 1, 2023, 21-35. doi: 10.21608/odr.2023.171707.1019
15. Iman A.M. Abdel-Rahman, Eman Zekry Attia, Omar M. Aly, Hani Saber, Mohammed I. Rushdi, Usama Ramadan Abdelmohsen, Metabolite profiling of green algae Halimeda opuntia to target hepatitis C virus-796 polymerase inhibitors assisted by molecular docking, South African Journal of Botany, Volume 151, Part A, 2022, Pages 538-543,
16. https://doi.org/10.1016/j.sajb.2022.10.038.
17.  Eman Zekry Attia, Basma Ali Khalifa, Gehan M. Shaban, Mohamed N. Amin, Lina Akil, Ibrahim Khadra, Ahmed A. Al Karmalawy, Radwan Alnajjar, Marco Y.W. Zaki, Omar M. Aly, Mo'men H. El-Katatny, Usama Ramadan Abdelmohsen, Potential topoisomerases inhibitors from Aspergillus terreus using virtual screening, South African Journal of Botany, Volume 149, 2022,Pages 632-645,
18. https://doi.org/10.1016/j.sajb.2022.06.051.
19.  Mai A. E. Mourad; Omar M. Aly; Ahmed A. E. Mourad. "Nitric oxide: Synthesis, Pathophysiology and Application on Oncology and Cardiovascular Diseases". Octahedron Drug Research, 1, 1, 2022, 34-49. doi: 10.21608/odr.2022.154048.1001
20. Mahmoud Mohamed; Omar M. Aly; Saleh Abdullah Alghamdi; Ali Alquraini; Abdulaziz Alzahrani; Adel Alghamdi; Ibrahim M. Shatla; Abd El Nasser El Shorbagi; Sachin Chaudhary; Muhamad Mustafa. "Phytochemical and in silico study on Lupinus subcarnosus Hook, its effect on neuronal α4β2 nicotinic acetylcholine receptors (nAChRs) and the major alkaloids". Octahedron Drug Research, 1, 1, 2022, 50-54. doi: 10.21608/odr.2022.155742.1007
21. Muhamad Mustafa; Yaser A. Mostafa; Atef E. Abd Elbaky; Mahmoud Mohamed; Dalia Abdelhamid; ElShimaa M. N. Abdelhafez; Omar M. Aly. "Combretastatin A-4 analogs: Past, present, and future directions". Octahedron Drug Research, 1, 1, 2022, 55-64. doi: 10.21608/odr.2022.156180.1008
22. Hassanin, Moamen A., Muhamad Mustafa, Mohammed A. S. Abourehab, Heba A. Hassan, Omar M. Aly, and Eman A. M. Beshr. 2022. "Design and Synthesis of New Hydantoin Acetanilide Derivatives as Anti-NSCLC Targeting GFRL858R/T790M Mutations" Pharmaceuticals 15, no. 7: 857. https://doi.org/10.3390/ph15070857
23. Heba Ali Hassan, Usama Ramadan Abdelmohsen, Omar M. Aly, Samar Y. Desoukey, Khaled M. Mohamed & Mohamed S. Kamel (2022) Potential of Ficus microcarpa metabolites against SARS-CoV-2 main protease supported by docking studies, Natural Product Research, 36:4, 994-998, DOI: 10.1080/14786419.2020.1839452
24. Eltamany, Enas E., Sameh S. Elhady, Marwa S. Goda, Omar M. Aly, Eman S. Habib, Amany K. Ibrahim, Hashim A. Hassanean, Usama Ramadan Abdelmohsen, Martin K. Safo, and Safwat A. Ahmed. 2021. "Chemical Composition of the Red Sea Green Algae Ulva lactuca: Isolation and In Silico Studies of New Anti-COVID-19 Ceramides" Metabolites 11, no. 12: 816. https://doi.org/10.3390/metabo11120816
25.  Amany E. Nofal, Ibrahim M. Shatla, Dalia A. Abdelhafeez, Muhamad Mustafa, Omar M. Aly, OMA1520 and OMA1774, novel 1,2,4-triazole bearing analogs of combretastatin A-4, inhibit hepatocellular carcinoma: Histological and immunohistochemical studies, Biomedicine & Pharmacotherapy, Volume 138, 2021, 111417, https://doi.org/10.1016/j.biopha.2021.111417.
26. Owis AI, El-Hawary MS, El Amir D, Refaat H, Alaaeldin E, Aly OM, Elrehany MA, Kamel MS. Flavonoids of Salvadora persica L. (meswak) and its liposomal formulation as a potential inhibitor of SARS-CoV-2. RSC Adv. 2021 Apr 12;11(22):13537-13544. doi: 10.1039/d1ra00142f.
27. Adel A. Marzouk, Amr K.A. Bass, Montaser Sh. Ahmed, Antar A. Abdelhamid, Yaseen A.M.M. Elshaier, Asmaa M.M. Salman, Omar M. Aly, Design, synthesis and anticonvulsant activity of new imidazolidindione and imidazole derivatives, Bioorganic Chemistry, Volume 101, 2020, 104020, https://doi.org/10.1016/j.bioorg.2020.104020
28. Aly O. Molecular Docking Reveals the Potential of Aliskiren, Dipyridamole, Mopidamol, Rosuvastatin, Rolitetracycline and Metamizole to Inhibit COVID-19 Virus Main Protease. ChemRxiv. 2020; doi:10.26434/chemrxiv.12061302.v1
29. El Hawary SS, Khattab AR, Marzouk HS, El Senousy AS, Alex MGA, Aly OM, Teleb M, Abdelmohsen UR. In silico identification of SARS-CoV-2 spike (S) protein-ACE2 complex inhibitors from eight Tecoma species and cultivars analyzed by LC-MS. RSC Adv. 2020 Nov 26;10(70):43103-43108. doi: 10.1039/d0ra08997d.
30. Abd El-Mordy FM, El-Hamouly MM, Ibrahim MT, El-Rheem GA, Aly OM, Abd El-Kader AM, Youssif KA, Abdelmohsen UR. Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening. RSC Adv. 2020 Aug 28;10(53):32148-32155. doi: 10.1039/d0ra05679k. 
31. Owis AI, El-Hawary MS, El Amir D, Aly OM, Abdelmohsen UR, Kamel MS. Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease. RSC Adv. 2020 May 21;10(33):19570-19575. doi: 10.1039/d0ra03582c.
32. Conference Paper, May 2022, Conference: 14th International Phytocosmetics and Phytotherapy Congress (IPPC), At: Egypt, Hepatitis C Virus -796 Protease Inhibitors
33. Raed M. Maklad, El-Shimaa M.N. AbdelHafez, Dalia Abdelhamid, Omar M. Aly, Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker, Bioorganic Chemistry, Volume 99, 2020, 103767,https://doi.org/10.1016/j.bioorg.2020.103767.
34. Muhamad Mustafa, Sirajudheen Anwar, Firgani Elgamal, Esam R. Ahmed, Omar M. Aly, Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study, European Journal of Medicinal Chemistry, Volume 183, 2019,111697, https://doi.org/10.1016/j.ejmech.2019.111697.
35. Alshimaa M.A. Aboeldahab, Eman A.M. Beshr, Mai E. Shoman, Safwat M. Rabea, Omar M. Aly,Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation, European Journal of Medicinal Chemistry, Volume 146, 2018, Pages 79-92, https://doi.org/10.1016/j.ejmech.2018.01.021.
36. Abuelhassan, A.H., Badran, M.M., Hassan, H.A. et al. Design, synthesis, anticonvulsant activity, and pharmacophore study of new 1,5-diaryl-1H-1,2,4-triazole-3-carboxamide derivatives. Med Chem Res 27, 928–938 (2018). https://doi.org/10.1007/s00044-017-2114-4.
37. Muhamad Mustafa, Dalia Abdelhamid, ElShimaa M.N. Abdelhafez, Mahmoud A.A. Ibrahim, Amira M. Gamal-Eldeen, Omar M. Aly, Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues, European Journal of Medicinal Chemistry, Volume 141, 2017,Pages 293-305, https://doi.org/10.1016/j.ejmech.2017.09.063.
38. Zaki, I., Ramadan, M., Abdelrahman, M.H. et al. Synthesis, cytotoxicity, and docking study of novel 1-naphthyl-5-aryl-1H-1,2,4-triazole-3-carboxamides. Monatsh Chem 148, 1483–1496 (2017). https://doi.org/10.1007/s00706-016-1910-8
39. Esam M. Aboubakr, Ashraf Taye, Omar M. Aly, Amira M. Gamal-Eldeen, Mohamed A. El-Moselhy, Enhanced anticancer effect of Combretastatin A-4 phosphate when combined with vincristine in the treatment of hepatocellular carcinoma, Biomedicine & Pharmacotherapy, Volume 89, 2017, Pages 36-46, https://doi.org/10.1016/j.biopha.2017.02.019.
40.  
41.  Shoman ME, Aly OM. Nitroxyl (HNO): A Possible Strategy for Fighting Cancer. Curr Top Med Chem. 2016;16(22):2464-70. doi: 10.2174/1568026616666160212123006. 
42. Abbas SH, Abuo-Rahma Gel-D, Abdel-Aziz M, Aly OM, Beshr EA, Gamal-Eldeen AM. Synthesis, cytotoxic activity, and tubulin polymerization inhibitory activity of new pyrrol-2(3H)-ones and pyridazin-3(2H)-ones. Bioorg Chem. 2016 Jun;66:46-62. doi: 10.1016/j.bioorg.2016.03.007. 
43. Hadimani MB, Mukherjee R, Banerjee R, Shoman ME, Aly OM, King SB. Ring expansions of acyloxy nitroso compounds. Tetrahedron Lett. 2015 Oct 21;56(43):5870-5873. doi: 10.1016/j.tetlet.2015.09.002. 
44. Abdel-Aziz M, Metwally KA, Gamal-Eldeen AM, Aly OM. 1,3,4-oxadiazole-2-thione Derivatives; Novel Approach for Anticancer and Tubulin Polymerization Inhibitory Activities. Anticancer Agents Med Chem. 2015;16(2):269-77. doi: 10.2174/1871520615666150907093855.
45. Abdel-Aziz M, Beshr EA, Abdel-Rahman IM, Ozadali K, Tan OU, Aly OM. 1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity. Eur J Med Chem. 2014 Apr 22;77:155-65. doi: 10.1016/j.ejmech.2014.03.001.
46. El-Shimaa M. N. AbdelHafez, Omar M. Aly, Gamal El-Din A. A. Abuo-Rahma, S. Bruce KingAdvanced Synthesis and Catalysis,  356, 3456 – 3464, 2014, Lossen Rearrangements under Heck Reaction Conditions. https://doi.org/10.1002/adsc.201400170
47. Aly OM, Beshr EA, Maklad RM, Mustafa M, Gamal-Eldeen AM. Synthesis, cytotoxicity, docking study, and tubulin polymerization inhibitory activity of novel 1-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxanilides. Arch Pharm (Weinheim). 2014 Sep;347(9):658-67. doi: 10.1002/ardp.201400096.
48. Mitroka S, Shoman ME, DuMond JF, Bellavia L, Aly OM, Abdel-Aziz M, Kim-Shapiro DB, King SB. Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide reductase subunit C. J Med Chem. 2013 Sep 12;56(17):6583-92. doi: 10.1021/jm400057r. 
49. AbdelHafez EM, Diamanduros A, Negureanu L, Luy Y, Bean JH, Zielke K, Crowe B, Vasilyeva A, Clodfelter JE, Aly OM, Abuo-Rahma GE, Scarpinato KD, Salsbury FR Jr, King SB. Computational and synthetic studies towards improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment. Mol Cancer Biol. 2013;1(1):44. 
50. Abdel-Aziz M, Aly OM, Khan SS, Mukherjee K, Bane S. Synthesis, cytotoxic properties and tubulin polymerization inhibitory activity of novel 2-pyrazoline derivatives. Arch Pharm (Weinheim). 2012 Jul;345(7):535-48. doi: 10.1002/ardp.201100471.
51. Shoman ME, Abdel-Aziz M, Aly OM, Farag HH, Morsy MA. Synthesis and investigation of anti-inflammatory activity and gastric ulcerogenicity of novel nitric oxide-donating pyrazoline derivatives. Eur J Med Chem. 2009 Jul;44(7):3068-76. doi: 10.1016/j.ejmech.2008.07.008.
52. Idrees GA, Abuo-Rahma Gel-D, Aly OM, Radwan MF. Design, synthesis and hypolipidemic activity of novel 2-(m-tolyloxy) isobutyric acid derivatives. Eur J Med Chem. 2009 Jun;44(6):2679-84. doi: 10.1016/j.ejmech.2008.12.009. European J of Medicinal Chemistry Volume 44, Issue 10, Pages 3973-3980, 2009 Design, Synthesis and Hypolipidemic Activity of Novel 2-(Naphthalen-2-yloxy)propionic Acid Derivatives as Desmethyl Fibrate Analogs
53. Metwally K, Aly O, Aly E, Banerjee A, Ravindra R, Bane S. Synthesis and biological activity of 2,5-diaryl-3-methylpyrimido[4,5-c]quinolin-1(2H)-one derivatives. Bioorg Med Chem. 2007 Mar 15;15(6):2434-40. doi: 10.1016/j.bmc.2007.01.016.
54. Idrees GA, Aly OM, Abuo-Rahma Gel-D, Radwan MF. Design, synthesis and hypolipidemic activity of novel 2-(naphthalen-2-yloxy)propionic acid derivatives as desmethyl fibrate analogs. Eur J Med Chem. 2009 Oct;44(10):3973-80. doi: 10.1016/j.ejmech.2009.04.026.
55. K Metwally, OM Aly, Sameh El-Nabtity, Spirohydantoins derived from 1-tetralone: design, synthesis and exploration of their anticonvulsant activity and neurotoxicity, Bulletin Faculty of pharmacy, Cairo university, 45, 149-154, 2007.
56. El-Sadek, M., El-Shanawany, A., Ali, O. COLORIMETRIC DETERMINATION OF SOME FLUOROQUINOLONE DERIVATIVES. Zagazig Journal of Pharmaceutical Sciences, 1995; 4(2): 157-162. doi: 10.21608/zjps.1995.186269
57. Alex. J. Pharm. Sci. 2135-48, 2007. Spectrophotometric Determination of Some Non-Steroidal Anti-Inflammatory Drugs
58. Azhar J. Pharm. Sci., 37 91-97, 2008. HPLC Determination of Fosinopril in Presence of Some of its manufacturing Impurities and Hydrochlorthiazide.
59. Azhar J. of Pharm. Sci., (37), 98 – 106, 2008. Colorimetric Determination of Levofloxacin and Moxifloxacin through Ion Pair Complex Formation with Metanil Yellow and Methyl Orange
60. Omar M. Aly, Colrimetric Determination of  N-Acetylcysteine through Reduction of Tetrazolium Salts, Azhar J. of Pharm. Sci., 37 83 – 90, 2008,
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